Front Cover; Nanotechnology in Cancer; Copyright Page; Contents; Contributors; About the Authors; Foreword; Preface; Introduction to Bio-Nanotechnology; 1 Gold nanoparticles for noninvasive radiofrequency cancer hyperthermia; Introduction; Brief Overview of Clinically Available Hyperthermia Systems; Nanoparticle-Mediated Cancer Hyperthermia; RF Interactions With AuNPs; Theoretical Frameworks for RF-Induced AuNP Heating; Joule Model; Classical and Quantum Electromagnetic Theory; Electrophoretic Model; Biological RF Activity of AuNPs In Vitro/In Vivo; Conclusion; References.
2 Silk fibroin nanoparticles and cancer therapyIntroduction; Materials and Methods; Materials; Cell Culture; Preparation of SF Solution and Curcumin Solution; Preparation of SF Nanoparticles and Curcumin-Loaded SF Nanoparticles; Characterization of Curcumin-Loaded SF Nanoparticles; Scanning electron microscopy; Atomic force microscopy; Dynamic light scattering; Drug loading efficiency; Curcumin release profile from SF nanoparticles; Biological Evaluation of Curcumin-Loaded SF Nanoparticles; Curcumin efficacy against GILM2 metastatic breast cancer cells.
Protein expression analysis using protein arrayStatistics; Results; Characterization of Curcumin-Loaded SF Nanoparticles; Morphology of curcumin-loaded SF nanoparticles; Particle size distribution of curcumin-loaded SF nanoparticles; Drug loading efficiency and release kinetics of curcumin from SF nanoparticles; Biological Evaluation of Curcumin-Loaded SF Nanoparticles; Curcumin efficacy against GILM2 metastatic breast cancer cells; Protein array analysis of apoptotic pathways activated by curcumin; Discussion; Conclusions; Acknowledgments; References; 3 Animal models in cancer nanotechnology.
Nanoparticles' Use in PharmacokineticsNanoparticles as Diagnostic Imaging Tools; Nanoparticles as a Theranostic Tool; Nanoparticles as a Treatment Tool; Conclusions; References; 4 Surgical implications of surface texturing in breast implants; Introduction; Capsular Contraction; The Cellular Response to Implant Surface Texturing; The Textured Implant: History and Development; The Silicone Shell; Salt Loss Technique; Stamping Technique; Surface Texturing and Cellular Ingrowth; Utility of Nanotechnology; Three-Dimensional Surface Printing; Surface Nanoparticles and Infection Prevention.
ConclusionReferences; 5 Nanoscale engineering of silk fibroin scaffold architecture to repair patient-specific cancer defects; Introduction; Materials and Methods; Scaffold Preparation; SF Solution Particle Size Measurement Using DLS; 3D Architecture Characterization Using SEM; Porosity Measurement; Mechanical Properties Measurement Using Uniaxial Tensile Testing; Conformation Analysis Using FTIR; Statistical Analysis; Results; Effect of SF Concentration on SF Particle Size in Solution; Effect of SF Concentration on SF Scaffold Properties; Effect of the Filter Size on SF Scaffold Properties.
