After modern science turns every human into a genetic time bomb with men dying at age twenty-five and women dying at age twenty, girls are kidnapped and married off in order to repopulate the world.

In a future where genetic engineering has cured humanity of all diseases and defects but has also produced a virus that kills all females by age twenty and all males by the age twenty-five, teenaged Rhine escapes her forced marriage and journeys back to New York to find her twin brother.