After being transported into medival Japan, Kagome discovers that her destiny links her to a powerful jewel of Four Souls and also to a half man, half dog demon named Inuyasha.

Inuyasha and the others try to break Tsubaki's evil spell and gain possession of the powerful jewel of the Four Souls.

They say that if one consumes mermaid flesh, one can attain immortality. Unfortunately, the more likely results include becoming horribly deformed or turning into a vicious monster! Even if one were to gain eternal life, however, is such an anomaly a lucky blessing or a terrible curse? Yuta became immortal when he unwittingly ate mermaid flesh, and now he seeks a way to become human again. Hundreds of years later, he encounters a volatile and determined...

Furinkan High gets a new principal with some very radical ideas about student discipline and a rather unexpected relationship with a blustering upperclassman Kuno. The poor, lovesick Ryoga finally gets a break when a magical bar of soap cures his porcine transformations.

"When Nanoka is transported back in time to a supernatural early 20th century, she gets recruited by aloof exorcist Mao. What thread of fate connects them? Together, they seek answers...and kick some demon butt along the way! Nanoka, Mao, and his helper Otoya investigate the strange cult of Priestess Shoko in hopes of bringing her to justice, but cursed dolls and scrolls of eternal life may be more than they bargained for. Will the priestess's doomsday...

Kagura has long sought to be free of her evil master's grasp, and when it appears that Naraku's powers have weakened, she plans her escape. But, afraid to take such a dangerous gamble alone, she tries to enlist Sesshomaru's help by offering him the jewel shards she stole from Koga's legs. Meanwhile, Naraku's newest incarnation is slaughtering humans and stealing their faces! What is this Faceless Man after, and how does he know Kagome?

Inyasha and the others come upon a temple that is inhabited by a false mentor who feeds upon those who want to become sages. Plus, when Kagome is captured during the full moon, will Inuyasha be able to rescue her without his powers?

Kagome seems like an ordinary high school girl ... until she's transported to medieval Japan and discovers that her destiny links her to the powerful Jewel of Four Souls and to a half-man, half-dog-demon named Inuyasha! Dark priestess Tsubaki was once Kikyo's rival for Keeper of the Sacred Jewel. Now, unable to forgive and consumed by her ambition to control the jewel, she uses a shard in her eye to devour demons and gain their power--and Inuyasha...

Can Inuyasha and Koga the wolf put aside their differences long enough to join forces against Naraku's new incarnations, Juromara and Kageromaru?

As the battle continues against Muso, who seems to be an incarnation of Naraku but not under Naraku's control, Muso sees Kagome and begins experiencing memories involving Inuyasha and Kikyo.